TOPLINE: In patients with locally advanced rectal cancer who receive neoadjuvant therapy, radiation dose intensification improves pathologic complete response but leads to a small increase in […]
TOPLINE: The response time to tumour necrosis factor (TNF) inhibitors in patients with psoriatic arthritis is influenced by the location of the affected joint. The shoulder […]
TOPLINE: Slower gait speed is independently associated with an increased risk for cardiovascular death or worsening heart failure in patients with stable heart failure with reduced […]
TOPLINE: Patient-directed educational brochures show promise in increasing the likelihood of deprescribing discussions and promoting shared decision-making; however, this approach is less effective in Black patients, […]
TOPLINE: Intravenous thrombolysis (IVT) administered within 4.5 hours was linked to significantly lower risk for neurological deterioration in acute pontine infarction than other antithrombotic therapies, new […]
TOPLINE: Adults using medically recommended cannabis have a higher prevalence of cannabis use disorder (CUD) and greater frequency of use than those using cannabis solely for […]
TOPLINE: In patients with ERBB2-positive metastatic breast cancer (ERBB2+ MBC) and brain metastasis, more than half of deaths were due to central nervous system (CNS)–related causes; […]
TOPLINE: COVID-19 vaccination is associated with a reduced risk for hyperthyroidism in the initial months postimmunization, but it is associated with an increased risk for hypothyroidism […]
TOPLINE: Romosozumab for 12 months followed by alendronate for 24 months leads to greater improvements in lumbar spine bone density and trabecular bone scores than alendronate […]
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