February 7, 2025
TOPLINE: A urinary DNA methylation test demonstrated high sensitivity and specificity for detecting high-grade or invasive bladder cancer, outperforming both nuclear matrix protein 22 (NMP22) and […]
February 7, 2025
TOPLINE: Zenocutuzumab demonstrates efficacy in patients with Neuregulin 1 (NRG1) fusion–positive cancer, achieving a 30% response rate across multiple tumor types. The bispecific antibody shows particularly […]
February 7, 2025
TOPLINE: Optical spectral transmission (OST) demonstrates a strong correlation with MRI in detecting joint inflammation in patients with inflammatory arthritis, with the best diagnostic performance observed […]
February 7, 2025
TOPLINE: A review of the top 50 TikTok videos about spironolactone for treating acne revealed that most were patient testimonials, with overall poor reliability and quality […]
February 7, 2025
TOPLINE: At least nine patients using the glucagon-like peptide 1 (GLP-1) receptor agonists semaglutide and tirzepatide developed ophthalmic complications, of whom seven had nonarteritic anterior ischemic […]
February 6, 2025
TOPLINE: Oral use of guanfacine by children and adolescents newly diagnosed with attention-deficit/hyperactivity disorder (ADHD) increases corneal aberrations but does not affect other ocular parameters. METHODOLOGY: […]
February 6, 2025
TOPLINE: A personalized cancer vaccine targeting neoantigens in high-risk renal cell carcinoma (RCC) demonstrates promising results, with no disease recurrence in any of the nine participants […]
February 6, 2025
TOPLINE: First trimester maternal 25-hydroxyvitamin D (25(OH)D) concentrations below 40 nmol/L are associated with 4.35 times higher risk for preterm birth. Higher first trimester 25(OH)D levels […]
February 6, 2025
TOPLINE: Pathologic complete response shows poor surrogacy for overall survival (OS) in neoadjuvant breast cancer (BC) trials, while invasive disease-free survival demonstrates moderate to strong association […]
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