March 28, 2025
TOPLINE: A higher body mass index (BMI) across all ages as well as significant weight gain during adulthood were associated with a greater risk for renal […]
March 27, 2025
For years, the default definitive treatment for patients with early-stage I non–small cell lung cancer (NSCLC) has been surgical resection, typically minimally invasive lobectomy with systematic […]
March 27, 2025
TOPLINE: A mailed fecal immunochemical test (FIT) outreach followed by patient navigation for those with a positive test increased colorectal cancer (CRC) screening participation at 6 […]
March 27, 2025
The US Food and Drug Administration (FDA) has approved cabozantinib (Cabometyx, Exelixis, Inc.) for certain adults and children aged ≥ 12 years with previously treated, well-differentiated […]
March 26, 2025
TOPLINE: Cancer drugs with higher clinical benefit in pivotal trials and without major safety concerns achieve full US Food and Drug Administration (FDA) approval more quickly. […]
March 26, 2025
TOPLINE: Surgical delay beyond 42 days after breast cancer diagnosis led to exponential growth in mortality risk for patients with hormone receptor–positive/human epidermal growth factor receptor […]
March 26, 2025
Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of refractory or relapsed leukemia and hematologic malignancies, particularly over the past decade. Despite its unprecedented […]
March 26, 2025
TOPLINE: A recent analysis found that neoadjuvant chemoimmunotherapy led to higher 2-year overall survival and disease-free survival (DFS) rates than neoadjuvant chemoradiotherapy in patients with locally […]
March 26, 2025
TOPLINE: Scientists at Johns Hopkins Medicine, Baltimore, have identified a potential new gene target, FLT1, that could be edited to treat sickle cell disease, an inherited […]